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BioAtla Says FDA Clears IND Application For BA3361 For The Treatment Of Multiple Tumors

RTTNews | vor 197 Tagen

BioAtla Says FDA Clears IND Application For BA3361 For The Treatment Of Multiple Tumors

(RTTNews) - Biotechnology company BioAtla, Inc. (BCAB) announced Monday that the U.S. Food and Drug Administration (FDA) has cleared its investigational new drug (IND) application to evaluate BA3361 (CAB-Nectin-4) antibody drug conjugate (ADC) for the treatment of multiple tumor types.

ADC is a promising treatment modality with broad applicability across multiple tumor indications. The CAB technology is designed to eliminate or reduce both on-target, off-tumor and off-target, off-tumor toxicities.

BA3361, CAB-Nectin4-ADC, is a conditionally and reversibly active antibody drug conjugate directed against Nectin4, a cell-cell adhesion molecule overexpressed in multiple human malignancies.

BA3361 is the first molecule containing one of BioAtla's novel NextGen ADC linkers with improved stability and tumor specific payload release. BA3361 showed superior activity in patient-derived pancreatic cancer xenograft models.

Tags: BCAB

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Canadian Market Recovers Well After Early Setback

Canadian Market Recovers Well After Early Setback

The Canadian market, which slid in early trades Tuesday morning on hot inflation data, and rising geopolitical concerns following an escalation in Russia - Ukraine war, recovered lost ground subsequently with a few frontline stocks finding some solid support at lower levels.

RTTNews | vor 5Std 30 Minuten

U.S. Housing Starts Tumble 3.1% In October, More Than Expected

U.S. Housing Starts Tumble 3.1% In October, More Than Expected

New residential construction in the U.S. tumbled by more than expected in the month of October, according to a report released by the Commerce Department on Tuesday. The report said housing starts dove by 3.1 percent to an annual rate of 1.311 million in October after slumping by 1.9 percent to a revised rate of 1.353 million in September.

RTTNews | vor 8Std 5 Minuten

U.S. Housing Starts Tumble More Than Expected In October

U.S. Housing Starts Tumble More Than Expected In October

New residential construction in the U.S. tumbled by more than expected in the month of October, according to a report released by the Commerce Department on Tuesday.

RTTNews | vor 9Std 3 Minuten

Eurozone Inflation Rises To 2% As Estimated

Eurozone Inflation Rises To 2% As Estimated

Eurozone inflation returned to the 2 percent target in October, final data from Eurostat showed on Tuesday. The harmonized index of consumer prices climbed as initially estimated in October after rising 1.7 percent in September. Core inflation that excludes prices of energy, food, alcohol and tobacco, remained unchanged at 2.7 percent in October.

RTTNews | vor 9Std 23 Minuten

Bay Street Seen Opening Lower On Geopolitical Concerns; Canadian Inflation Data In Focus

Bay Street Seen Opening Lower On Geopolitical Concerns; Canadian Inflation Data In Focus

Canadian shares look headed for a weak start on Tuesday amid rising geopolitical concerns after Russian President Vladimir Putin updated nuclear doctrine.

RTTNews | vor 9Std 47 Minuten

Euro Slides Against Majors

Euro Slides Against Majors

The euro weakened against other major currencies in the European session on Tuesday, as traders are worried that protectionist policies by President-elected Donald Trump could disrupt the Eurozone's growth potential.

RTTNews | vor 9Std 53 Minuten

FTSE 100 Slips As Geopolitics Weighs

FTSE 100 Slips As Geopolitics Weighs

The FTSE 100 benchmark of the London Stock Exchange aligned with the trend in European markets to trade in the red amidst a massive spike in geopolitical concerns. However, the index managed to outperform its European peers.

RTTNews | vor 9Std 57 Minuten

European Stocks Tumble As Russia-Ukraine War Hurts Sentiment

European Stocks Tumble As Russia-Ukraine War Hurts Sentiment

European stocks are reeling under a bout of selling pressure on Tuesday following an escalation in the Russia - Ukraine war, and amid uncertainty about U.S. interest-rate trajectory and the outlook for global economic growth.

RTTNews | vor 10Std 6 Minuten

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