RedHill Says Its Oral Antivirals, Opaganib And RHB-107, Inhibit Dominant Omicron Sub-Variant BA.5

RTTNews | 938 days ago
Stocktwits
RedHill Says Its Oral Antivirals, Opaganib And RHB-107, Inhibit Dominant Omicron Sub-Variant BA.5

(RTTNews) - Specialty biopharmaceutical company RedHill Biopharma Ltd. (RDHL) announced Monday the study results showing in vitro efficacy against the currently dominant Omicron COVID-19 sub-variant BA.5, by both of RedHill's novel, oral, host-directed and broad-acting investigational antivirals, once-daily RHB-107 (upamostat) and twice-daily opaganib.

These results build on previously reported data on the inhibition of COVID-19, variants of concern and other viruses, and further support their broad-acting, host-directed mechanisms of action.

The company tested RHB-107 and opaganib using a primary human nasal epithelial cell culture model of Omicron BA.5, which was specifically selected due to the high level of SARS-CoV-2 entry factor expression in these cells. The results show that both RHB-107 and opaganib inhibit Omicron sub-variant BA.5 viral replication, which is indicative of antiviral activity.

The development of both opaganib for hospitalized patients and RHB-107 for non-hospitalized patients is ongoing, including ongoing and planned pandemic preparedness research collaborations with US governmental agencies, pivotal Phase 3 trial design and regulatory clearances, and securing of external non-dilutive funding.

Tags: RDHL
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European Shares Edge Higher In Cautious Trade

European Shares Edge Higher In Cautious Trade

European stocks traded higher on Monday as tariff tensions eased and investors looked ahead to a busy week of earnings, with four of the Magnificent Seven companies— Amazon, Apple, Meta Platforms and Microsoft — due to report their quarterly results.
RTTNews | 15 minutes ago
European Shares Seen Opening Up In Cautious Trade

European Shares Seen Opening Up In Cautious Trade

European stocks are likely to open on a steady note Monday after U.S. stocks posted their longest advance in three months on Friday amid signs of easing trade tensions and bets the Federal Reserve will cut interest rates as early as June, as the American economy softens.
RTTNews | 3h 39min ago
Sensex, Nifty Follow Global Peers Higher

Sensex, Nifty Follow Global Peers Higher

Indian shares were trading higher on Monday, tracking firm cues from global markets. The benchmark S&P/BSE was up 548 points, or 0.7 percent, at 79,760 despite rising tensions between India and Pakistan, triggered by the Pahalgam terror attack.
RTTNews | 4h 55min ago
Australian Market Trims Early Gains In Mid-market

Australian Market Trims Early Gains In Mid-market

The Australian stock market is trimming its early gains in mid-market trading on Monday, adding to the gains in the previous two sessions, following the broadly positive cues from Wall Street on Friday. The benchmark S&P/ASX 200 index is moving well above the 8,000.00 mark, with gains technology, energy and financial stocks partially offset by weakness in mining stocks.
RTTNews | 5h 53min ago
Asian Markets Track Wall Street Higher

Asian Markets Track Wall Street Higher

Asian stock markets are trading mostly higher on Monday, following the broadly positive cues from Wall Street on Friday, on easing global trade tensions amid ongoing tariff talks between the US and some of its partner countries, including China and Japan. There are also hopes for additional stimulus measures in China aimed at offsetting the impact of US tariffs.
RTTNews | 6h 10min ago
Thai Stock Market May See Additional Support On Monday

Thai Stock Market May See Additional Support On Monday

The Thai stock market bounced higher again on Friday, one day after ending the two-day winning streak in which it had gained almost 20 points or 1.8 percent. The Stock Exchange of Thailand now sits just beneath the 1,160-point plateau and it's expected to extend open in the green again on Monday.
RTTNews | 7h 15min ago
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