Axsome Says Sunosi Met Primary Endpoint In SHARP Study

RTTNews | 913 days ago
Axsome Says Sunosi Met Primary Endpoint In SHARP Study

(RTTNews) - Biopharmaceutical company Axsome Therapeutics, Inc. (AXSM) announced Monday that Sunosi met the primary endpoint in the SHARP study and significantly improved cognitive function, measured using the Digit Symbol Substitution Test subtest of the Repeatable Battery for the Assessment of Neuropsychological Status (DSST RBANS), as compared to placebo in cognitively impaired patients with excessive daytime sleepiness (EDS) associated with obstructive sleep apnea (OSA).

Superiority of Sunosi as compared to placebo was further demonstrated using patient-reported measures of cognitive function. In the study, Sunosi replicated previous findings by significantly reducing EDS symptoms as compared to placebo.

SHARP (Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study) was a randomized, double-blind, placebo-controlled, crossover, multicenter, trial in 59 patients with EDS associated with OSA, and impaired cognitive function.

Patients were all treated with Sunosi for 2 weeks, and with placebo for 2 weeks, with the treatment periods separated by 1 week of down-titration and washout.

read more
FTSE 100 Sharply Lower As Trump's Tariff Announcement Hurts Sentiment

FTSE 100 Sharply Lower As Trump's Tariff Announcement Hurts Sentiment

U.K. stocks are languishing in negative territory after a weak start Thursday morning amid fears of a global trade war after U.S. President Donald Trump announced steep "reciprocal tariffs" on major trading partners. The British market's loss is somewhat less pronounced compared to other major European markets, as UK imports face a 10% tariff, half the 20% levy imposed on the European Union.
RTTNews | 4h 30min ago
Sensex, Nifty End Modestly Lower As IT Stocks Drag

Sensex, Nifty End Modestly Lower As IT Stocks Drag

Indian shares fell on Thursday after U.S. President Donald Trump announced a 10 percent universal tariff on most imported goods along with additional high tariffs on countries the U.S. considers "worst offenders" based on trade deficits and non-tariff barriers.
RTTNews | 4h 42min ago
CAC 40 Down Nearly 2.5% As Tumble On Trump's Tariff Announcement

CAC 40 Down Nearly 2.5% As Tumble On Trump's Tariff Announcement

French stocks are down sharply Thursday morning, mirroring losses in markets across Europe amid concerns about the impact of new tariffs announced by U.S. President Donald Trump. It is feared that the new levies could fuel inflation and disrupt global supply chains, and lead to trade wars.
RTTNews | 4h 56min ago
Amazon Places Bid For TikTok Ahead Of US Sale Deadline

Amazon Places Bid For TikTok Ahead Of US Sale Deadline

As the April 5 deadline is looming for TikTok, owned by China-based ByteDance Ltd, to find a buyer or to face shutdown in the United States, its biggest market, Amazon has entered the picture, submitting a takeover bid to the White House for the business, reports said. With this, the tech major joins the list of potential bidders including private equity firm Blackstone and mobile technology...
RTTNews | 5h 24min ago
European Shares Tumble On Tariff Jitters

European Shares Tumble On Tariff Jitters

European stocks fell sharply on Thursday as investors fretted about the potential repercussions of the new tariffs announced by U.S. President Donald Trump.
RTTNews | 6h 12min ago
Asian Shares Slide On Trade War Concerns

Asian Shares Slide On Trade War Concerns

Asian stocks tumbled on Thursday after U.S. President Donald Trump announced a 10 percent universal tariff on most imported goods along with additional high tariffs on countries the U.S. considers "worst offenders" based on trade deficits and non-tariff barriers.
RTTNews | 6h 35min ago
DAX Down Sharply Despite Coming Off Early Lows

DAX Down Sharply Despite Coming Off Early Lows

German stocks are down sharply Thursday morning due to heavy selling almost across the board as investors react to the U.S. government's announcement of "reciprocal tariffs." The much steeper-than-expected tariffs on US trade partners, has heightened concerns over a global trade war that could destabilize major economies.
RTTNews | 6h 35min ago
U.S. Dollar Drops Amid Fed Rate Cut Bets

U.S. Dollar Drops Amid Fed Rate Cut Bets

The U.S. dollar weakened against other major currencies in the European session on Thursday, as traders increase their bets that the Fed will lower rates in June, as Trump imposes fresh tariffs, traders increase their wagers that the Fed will lower rates in June.
RTTNews | 6h 39min ago